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《中国药理学与毒理学杂志》2019年10期

 
目录
大会报告
新时代中医药传承发展的机遇与挑战张伯礼;641-642
基于络病理论的中药新药研发吴以岭;642
中药多组分体内过程与药效关联研究的探索王广基;643
Targeting endothelial senescence by natural products to improve vascular healthValérie SCHINI-KERTH;643-644
Herbal formula enhances 5-fluorouracil activity through suppression of thymidylate synthaseLIU Hai-zhou;LIU Hui;ZHOU Zhi-yi;Robert A.PARISE;Edward CHU;John C.SCHMITZ;644-645
中西医结合研究诠释《神农本草经》有关灵芝的论述林志彬;645-646
做出中国新药的特色——小檗碱研究的思考蒋建东;646-647
Critical success factors for acceptance of multi-herbal Chinese medicine in EuropeWANG Mei;646-647
中药作用分子机制研究新策略王升启;647
中医药“异病同治”作用的分子生物学新解孙鹤;648
心脑缺血的防治策略与丹参及丹酚酸A的作用与机制杜冠华;王海港;宋俊科;张雯;刘成娣;刘楠楠;张莉;648-649
功能性胃肠病中药复方临床研究实践与思考张北华;唐旭东;649专题报告
从临床角度考虑维医药对溃疡性结肠炎的临床定位斯拉甫·艾白;阿不都外力·阿不都克里木;李治建;高莉;阿里甫·恩提;希尔艾力·吐尔逊;艾山江·司马义;胡拉木;阿不来提;650
基于“系统观”探讨中药复方研究的新思维和新方法陆茵;650-651
斑马鱼内毒素炎症模型建立及中药抗内毒素炎症研究周红玲;杨丽玲;刘东依;卢子滨;曹惠慧;刘俊珊;余林中;651
氧化与还原平衡:脑卒中神经保护和修复的治疗靶点及其在中医药应用沈剑刚;652
网络药理学与中成药再评价黄娜娜;孙蓉;653
中药外用疗效新机制苗明三;李孟艳;田硕;653-654
CA-30,an active fraction derived from Liuwei Dihuang Decoction,ameliorates cognitive deterioration via intestinal microbiomeZHOU Wen-xia;WANG Jian-hui;LEI Xi;ZHANG Xiao-rui;CHENG Xiao-rui;ZHANG Yong-xiang;654-655
西洋参茎叶总皂苷减轻模拟失重导致心肌重塑的作用研究孙慧媛;史大卓;655
有毒中药的毒效关系研究高月;655-656
中药有效成分的作用机制和物质基础张丹参;656
我国中药新药创制转化历程与药理学的作用赵军宁;鄢良春;戴瑛;华桦;曾瑾;李莉;尹竹君;张翼冠;657
青蒿素及其衍生物抗疟机制研究概况朱晓新;王继刚;657-658
Tetramethylpyrazine analogue T-006 promotes clearance of alpha-synuclein by enhancing proteasome activity in Parkinson disease modelsZHOU He-feng;SHAO Min;GUO Bao-jian;LI Chu-wen;LU Yu-cong;YANG Xuan-jun;LI Sheng-nan;LI Hai-tao;ZHU Qi;ZHONG Han-bing;WANG Yu-qiang;ZHANG Zai-jun;LU Jia-hong;LEE Ming-yuen Simon;658-659
调节性坏死与心脑损伤及女贞苷干预佘浪;张议月;刘斌;罗秀菊;彭军;659
丹红注射液治疗慢性稳定型心绞痛的靶点模块识别与多表型药理机制研究王忠;660
姜黄素在肿瘤治疗中的基础与临床研究和问题李学军;660-661
中药与天然药物的新药研究思路与实践刘建勋;661
来源于经典名方的中药新药高质量发展战略思考孙晓波;662
Pharmacophenomics and Fangjiomics:new pharmacological research paradigm in era of precision medicineDUAN Da-yue;YE Ling-yu;662-663
中药补益(保健)药理研究思考与思路吕圭源;663-664
中药复方大品种技术升级研究与培育的思路杨洪军;664青年论坛——青年学者
黄蜀葵花调控肠道菌群中尿毒素代谢通路干预慢性肾病进展的作用机制郭建明;665
Mechanisms of active fraction combination from Liuwei Dihuang Decoction(LW-AFC) on long-term potentiation impairment in vivoHUANG Yan;LI Dong;CHENG Bin;LIU Gang;ZHANG Yong-xiang;ZHOU Wen-xia;665
黄芪多糖RAP对巨噬细胞的激活及几种黄酮类化合物的干预作用李志鹏;666
创新降糖中药桑枝总生物碱调节肠-胰岛轴作用及机制初探刘率男;刘泉;李彩娜;环奕;刘志华;刘玉玲;谢明智;申竹芳;666-667
Reducing histone acetylation rescues cognitive deficits in mouse model of fragile X syndromeLI Yue;Michael E.STOCKTON;Brian E.EISINGER;ZHAO Ying-hua;Jessica L.MILLER;Ismat BHUIYAN;GAO Yu;WU Zhi-ping;PENG Jun-min;ZHAO Xin-yu;666
Myrrh extract alleviated ROS-mediated ferroptosis through regulating TXNIP/NLRP3 axis in ischemic strokeLIU Tian-long;WANG Wen-jun;DING Yi;WEN Ai-dong;ZHANG Ru-xue;667-668
基于粪便代谢组学的逍遥散抗抑郁作用机制刘晓节;吕梦;王雅泽;赵迪;赵思俊;李顺勇;秦雪梅;668
TCM-040抗心律失常作用及电生理机制苏敏;徐登峰;周璐恒;张晓佩;侯云龙;刘克剑;王宏涛;668-669
孟河医派特色炮制猪心血丹参及其他炮制品对大鼠脑缺血保护及PI3K/AKT信号通路的影响颜晓静;曹琰;黄玮;朱月琴;刘产明;曹震;张琪;669
CP-25 monotherapy and combined administration ameliorate progression of animal arthritis model by inhibition on GRK2 translocationYANG Xue-zhi;ZHAO Ying-jie;SU Su-li;WANG Chun;WU Yu-jing;ZHANG Ling-ling;CHANG Yan;WEI Wei;669-670
中药活性成分直接作用靶点“钩钓”技术的建立与应用曾克武;670
丹参多酚酸通过PI3K/Akt-JAK2/STAT3途径减轻大鼠脑缺血再灌注损伤张雯;宋俊科;杜冠华;670
复方中药塞络通对多发性脑梗死大鼠星形胶质细胞功能及脂笼蛋白2蛋白表达的影响张业昊;姚明江;刘建勋;671
Neuroprotection of total steroid saponins from Dioscorea zingiberensis C.H.Wright against transient focal cerebral ischemia-reperfusion injury in rats via its anti-inflammatory and anti-apoptotic effectsZHANG Xin-xin;WANG Xing-bin;ZHAN Guan-qun;GUO Zeng-jun;XIE Ren-ming;671
基于调控脑肠轴探索解毒化瘀汤改善阿尔茨海默病小鼠认知功能的机制张云龙;刘妍;徐评议;文磊;672
基于1H-NMR代谢组学及网络药理学方法研究罗勒黄酮类活性成分对ApoE-/-模型小鼠的影响周文婷;季志红;阿尔祖亚·多力空;阿地力江·萨吾提;艾尼瓦尔·吾买尔;672青年论坛——研究生
小檗碱通过调控溃疡性结肠炎肠道神经免疫炎症保护黏膜屏障损伤李恒;左建平;唐炜;673
山奈酚通过抑制神经炎症及保护血脑屏障而改善大鼠脑缺血再灌注神经功能李伟瀚;程笑;杨滢霖;刘漫;张姗姗;王月华;杜冠华;673
山楂叶黄酮类成分在糖脂代谢紊乱大鼠体内的代谢组学研究刘甜;周坤;王静静;韩伟;王栋梅;陈文君;马百平;郑晓辉;赵晔;674
千金藤素体外抗HSV-1的作用及机制初步研究刘鳐;唐琼;方洋;彭利霞;曾南;674
玉屏风散对小鼠胸腺上皮细胞介导的皮肤淋巴细胞功能的影响马丽;沈佳曼;郭文琴;高建莉;675
补骨脂酚通过上调上皮雌激素受体β和下调间质芳香化酶抑制大鼠良性前列腺增生齐雅馨;苗琳;焦婵媛;邵瑞;樊官伟;李小江;王跃飞;朱彦;张琚;高秀梅;675
目录
大会报告
医学科技中的伦理道德考量秦伯益;753
Pharmacogenomics in oncologyIngolf CASCORBI;753-754
Pharmacology and drug discoverySJ ENNA;754
Metabolic aspects behind ageing and neurodegeneration reveal new ways forward for therapy in motorneurone(ALS) and Parkinson diseasesA BOUSCARY;C QUESSADA;A HENRIQUES;JP LOEFFLER;M SPEDDING;754
肿瘤的精准治疗与挑战丁健;755
大脑觉醒及三代促清醒药物林建生;755青年英文报告和论文摘要_青年学者报告和论文摘要
Selective and robust UPLC-MS/MS method for simultaneous quantitative determination of anlotinib, ceritinib and ibrutinib in rat plasma and its application to pharmacokinetic studyDU Ping;GUAN Yin;AN Zhuo-ling;LI Peng-fei;LIU Li-hong;756
Bitter compounds delay gastric emptying while affecting plasma hormone profiles and duodenal nutrient absorption in a pig modelFU Ming-hai;Eugeni ROURA;David VAL-LAILLET;Genna BA;756-757
A semisynthetic cabazitaxel analogue, C1 overcomes P-gp-meditaed multidrug resistance in non-small-cell lung cancerJIA Li-na;TANG Xing;YANG Jing-yu;WU Chun-fu;757
Low expression programming of angiotensin receptor Ⅱ mediated pancreatic β cell dysfunction and glucose intolerance in prenatal dexamethasone-exposed female ratsKOU Hao;GUI Shu-xia;DAI Yong-guo;Guo Yu;WANG Hui;757-758
Potential role of histone deacetylase 3 specific inhibitor Compound A in diabetes treatmentLEI Lei;XIA Jie;LIU Quan;SUN Su-juan;LIU Shuai-nan;LI Cai-na;CAO Hui;HUAN Yi;SHEN Zhu-fang;758
Artemisinin analogue SM934 protects againstlupus-associated antiphospholipid syndromeinmale(NZW × BXSB) F1 mice via Nrf2/HO-1 pathwayLIN Ze-min;HE Shi-jun;LIU Yu-ting;TANG Wei;ZUO Jian-ping;758-759
Melatonin prevents endothelial cell pyroptosis via regulation of long noncoding RNA MEG3/miR-223/NLRP3 axisLIU Xin;ZHANG Yong;YANG Bao-feng;759-760
Multiple circulating saponins from intravenous Shenmai inhibit OATP1Bs in vitro: potential joint precipitants of drug interactionsOlajide E OLALEYE;NIU Wei;DU Fei-fei;WANG Feng-qing;XU Fang;Salisa PINTUSOPHON;LU Jun-lan;YANG Jun-ling;LI Chuan;760
Identification of SPP1 as an extracellular matrix signature for metastatic castration-resistant prostate cancerPANG Xiao-cong;XIE Ran;ZHANG Zhuo;LIU Qian-xin;WU Shi-liang;CUI Yi-min;760-761
Acute phase protein orosomucoid protects against heart failure through CCR5-mediated improvement in energy metabolism and calcium sensitivityQIN Zhen;SUN Yang;LIU Xia;SU Ding-feng;761
Mechanistic of Daxiepi Tang in treating lung cancer based on network pharmacologyREN Wei-yu;HUANG Rui;ZHENG Yi-jun;LIU Yong-qi;LIU Dong-ling;WEI Ben-jun;762
Chronic stress alters activity of insular cortex,leading to aberrant decision-makingSHI Tian-yao;ZHANG Yong-xiang;ZHOU Wen-xia;762
Remedial dosing recommendations for valproic acid in nonadherence patients with epilepsyWANG Chen-yu;DING Jun-jie;JIAO Zheng;ZHU Guo-xing;763
Shenmai injection attenuated doxorubicin-induced cardiac dysfunction via maintaining mitochondrial homeostasisWANG Qi-long;LI Lin;LI Jing-hao;YANG Dong-li;LI Yu-hong;763
Andrographolide derivative as anti-inflammation agent for treatment of inflammatory bowel diseaseWANG Ying;763-764
CP-25 ameliorates progression of animal arthritis model by inhibition on GRK2 translocationYANG Xue-zhi;ZHAO Ying-jie;SU Su-li;WANG Chun;WU Yu-jing;ZHANG Ling-ling;CHANG Yan;WEI Wei;764
Platelet-derived miR-223 promotes a phenotypic switch in arterial injury repairZENG Zhi;XIA Luo-xing;FAN Xue-jiao;TANG Wai-ho;764-765
Elevated progranulin contributes to synaptic and learning deficit due to loss of fragile X mental retardation proteinZHANG Kun;LI Yu-jiao;GUO Yan-yan;ZHENG Kai-yin;YANG Qi;YANG Le;CHEN Tao;ZHUO Min;ZHAO Ming-gao;765-766
Effects of purified fruit bromelain fractions on intestinal inflammatory diseasesCHEN Da-peng;Mohamed AZARKAN;766
Protease-activated receptor 2 modulating cancer cell signal transduction and functionsJIANG Yu-hong;766-767
Role of pleckstrin-2 in cancerLI Xiao-mei;SHEN Yue-mao;ZHAO Bao-bing;767
Bidirectional modulation of HIF-2 activity through allosteric ligandsWU Da-lei;SU Xiao-yu;LU Jing-ping;LI Sheng;Becky HOOD;Stefan VASILE;Nalini POTLURI;DIAO Xiao-tong;Young-chang KIM;Sepideh KHORASANIZADEH;Fraydoon RASTINEJAD;767-768
Up-regulated Piezo1 in VSMCs promotes pathological hemodynamic environment-mediated neointimal hyperplasiaZHANG Fei-ran;ZHOU Jia-guo;768
Effect of proteomics change of PTS on liver tissue potentially influence blood rheological properties in miceZHANG Hong-mei;YAO Wei-juan;TIAN Hui-kai;YU He-ming;LI Xue-jun;768-769
DP1 activation protects against injury-induced vascular neointima hyperplasia by suppressing autophagy-dependent microRNA-183 cluster expressionZHANG Jian;769
RhoC/ROCK2 promotes vasculogenic mimicry formation primarily through ERK/MMPs in hepatocellular carcinomaZHANG Ji-gang;ZHANG Xue;ZHOU He-ming;LI Qin;LIU Gao-lin;769-770
Enhancement of epithelial cell autophagy induced by sinensetin alleviates epithelial barrier dysfunction in colitisXIONG Yong-jian;QIU Juan-juan;GUO Hui-shu;770青年英文报告和论文摘要_研究生报告和论文摘要
Kanglexin, a novel anthraquinone compound,protects against myocardial ischemic injury in mice by suppressing NLRP3 and pyroptosisBIAN Yu;LI Xin;PANG Ping;WANG Ning;WANG Jin-hui;XIAO Wei;DU Wei-jie;YANG Bao-feng;770-771
LINC00152 upregulates ZEB1 to enhance epithelial-mesenchymal transition and oxaliplatin resistance by interacting with EZH2CHEN Shuang;XU Cheng-cheng;ZHAO Cheng-kuan;ZHANG Qiu-zhen;CHEN Yun;ZHANG Xiao-yan;LIAN Shan-shan;CHEN Chen;QIU Guo-dong;ZHANG Shu-yao;771
Ganoderic acid hinders renal fibrosis via suppressing TGF-β/Smad and MAPK signaling pathwaysGENG Xiao-qiang;771-772
ROCK1 inhibitor fasudil improves diabetic wound healing via AMPK/Drp1/eNOS pathwayHUYAN Tian-ru;SHI Yun-di;LI Xue-jun;TIE Lu;772
Inhibition of P2X7R modulates ECM deposition in HSCs and crosstalk with macrophages in liver fibrosisJIANG Min;CUI Ben-wen;ZHANG Yu;WU Yan-ling;NAN Ji-xing;LIAN Li-hua;772-773
Protect dextran sulfate sodium-induced ulcerative colitis in mice by neferine, a natural product from Nelumbo nucifera GaertnMIN Xiang-jing;LU Yuan-fu;SHI Jing-shan;CHEN Xiu-ping;773-774
Anexploration on potential mechanism of Shanhaidan Granules in treating erectile dysfunction based on network pharmacologyQIAN Cheng;CHENG Peng;ZHENG Wei-wei;YU Su-yun;WU Jia-wei;ZHENG Meng-kai;CHEN Wen-xing;LU Yin;WANG Ai-yun;774
LncRNA SPRY4-IT1 regulates breast cancer cell stemness through competitively binding miR-6882-3p with TCF7L2SONG Xin-yue;ZHANG Xiao-xue;WANG Xin-nan;CHEN Lian-ze;JIANG Long-yang;ZHENG Ang;ZHANG Ming;ZHAO Lin;WEI Min-jie;774-775
Nicotinic acetylcholine receptor α7 inhibits platelet-derived growth factor-induced migration of vascular smooth muscle cells by activating mitochondrial deacetylase SIRT3TONG Jie;LI Dong-jie;ZENG Fei-yan;GUO Meng-qi;LI Yong-hua;WANG Hong-bo;WANG Pei;775
Continuous culture of urine-derived bladder cancer cells for precision medicineWANG Jia-qi;JIANG Shuai;DANG Yong-jun;776
ATF3 promotes ferroptosis by suppressing system Xc~-WANG Li-yuan;LIU Yi-chen;DU Ting-ting;CHEN Xiao-guang;YAN Chun-hong;776-777
Impact of obese levels on hepatic expression of drug-metabolizing enzymes in adult and offspring miceWANG Pei;ZHONG Xiao-bo;ZHANG Li-rong;777
Phosphorylation site at serine 282 of connexin 43 has a regulatory effect on survival and apoptosis of cardiomyocytesYANG Yu-tong;YAN Xin-xin;XUE Jing-yi;778
Amiodarone induces autophagy/mitophagy by activating sirtuin-3 in acute myelocytic leukemiaZHANG Jin;SUN De-juan;ZHANG Lan;OU Yang-liang;778-779
Xenon exerts anti-seizure and neuroprotective effects in kainic acid-induced status epilepticus and neonatal hypoxia-induced seizureZHANG Meng-di;ZHANG Yu-rong;YU Jie;CUI Ya-ru;WANG Qiao-yun;SUN Hong-liu;779
Cytochalasins Q and 19, 20-epoxycytochalasin C exhibit anti-tumor activity in B16 melanoma cells via creatine metabolic pathwaysZHANG Peng;LU Yi;CHEN Hong-dan;WANG Jia;TONG Qing-yi;TIAN Cheng;YANG Jian;ZHANG Zi-jun;WANG Bao-tian;PENG Wen;XIANG Ming;779-780
Drug repurposing identifies econazole as a novel neuroprotective agent that activates autophagy/mitophagy in Parkinson disease modelsZHEN Yong-qi;ZHAO Yu-qian;FU Lei-lei;LIU Bo;780
Betulinic acid induces apoptotic and autophagic cell death in hepatocellular carcinomaCHEN Fei-yu;ZHONG Zhang-feng;TAN Hor-yue;WANG Ning;FENG Yi-bin;780-781
Anti-proliferation activity of total flavonoids isolated from Diospyros kaki L. f. leaves against human cancer celllinesCHEN Li;GAO Ying;GUO Yu-hang;Ghedal ALSAIF;781
Resistance of esophageal cancer cells to paclitaxel can be reduced by knockdown of long noncoding RNA DDX11-AS1 through TAF1/TOP2A inhibitionCHEN Wan-ying;XU Cheng-cheng;ZHAO Cheng-kuan;ZHANG Qiu-zhen;CHEN Yun;CHEN Si-hua;LI Li;SHE Yu-qi;ZHENG Jie-ting;ZHANG Shu-yao;781-782
Effect of all-trans retinoic acid on differentiation of osteosarcoma cellsCHEN Ying-qian;YANG Bo;HE Qiao-jun;YING Mei-dan;782
Acanthoic acid modulates lipogenesis in nonalcoholic fatty liver disease via FXR/LXRs-dependent mannerHOU Li-shuang;HAN Xin;CUI Zhen-yu;LIAN Li-hua;SONG Jian;WANG Ge;ZHENG Shuang;DONG Xiu-xiu;WU Yan-ling;NAN Ji-xing;783
Inhibition of PDE4 represents an infusive therapeutic strategy in ulcerative colitisLI Heng;ZUO Jian-ping;TANG Wei;783-784
Anovel BTK inhibitor SIMM-016, ameliorates rheumatoid arthritis by dual inhibition of BCR and osteoclastogenic signalingLIU Yu-ting;LIN Ze-min;HE Shi-jun;ZUO Jian-ping;784
Classic herb pair sculellaria barbata and hedyotis diffusa for breast cancer: potential mechanism with method of network pharmacologyMA Ting-ting;ZHANG Gan-lin;DAI Cun-fang;ZHANG Bo-ran;LI Bing-xue;ZHANG Jia-hui;WANG Xiao-min;784-785
Ganodermalucidum polysaccharide peptides attenuate post myocardial infarction fibrosis through down-regulating TGF-β1/SMAD signaling and ROS in mouse heartMENG Jia;785-786
Ginsenoside 25-OCH3-PPD promotes activity of LXRs to ameliorate P2X7R-mediated NLRP3 inflammasome in development of hepatic fibrosisSONG Jian;HAN Xin;CUI Zhen-yu;LIAN Li-hua;HOU Li-shuang;WANG Ge;ZHENG Shuang;DONG Xiu-xiu;NAN Ji-xing;WU Yan-ling;786
Role and mechanism of ORM in adipose tissue fibrosis and insulin resistance in obese miceWANG Peng-yuan;QIN Zhen;ZHANG Yu;FENG Jia-yi;HU Bo-han;WEI Jie;SU Ding-feng;SUN Yang;LIU Xia;786-787
Discovery and utilization of marine leading compounds in tumor immunityWANG Xiao-bo;HUANG Jing;ZHANG yuan-yuan;LUO Cheng;DANG Yong-jun;787
CDK2 suppressionsynergizes with all-transretinoic acid toovercome myeloid differentiation blockade of AML cellsXU Ai-xiao;XIANG Sen-feng;CHEN Ying-qian;SHI Xiao-xian;SHAO Xue-jing;YANG Bo;HE Qiao-jun;YING Mei-dan;788
Roles of Sirtuin family in non-small cell lung cancerZENG Chen-ming;HU Yan;CHANG Lin-lin;HE Qiao-jun;ZHU Hong;YANG Bo;788
Lipid metabolic reprogramming promotes hepatocarcinogenesis and targeted regulation of related drugsZHANG Cong;QIU Zhen-peng;ZHENG Guo-hua;788-789
Identification of a clinical compound losmapimod that blocks Lassa virus entryZHANG Xiao-yu;GUO Ying;789-790专题报告和论文摘要_临床药理学
磷酸二酯酶:从伟哥到抗阿尔茨海默病药物王浩;周延萌;侯雪芹;张芳芳;赵晓民;张汉霆;790
Evaluation of interventions by pharmacists in vancomycin treatment in Chinese adult pneumonia patients: a randomized controlled trialMA Ling-yun;YANG Ting;CHEN Chao-yang;GAO Fei-fei;QUE Cheng-li;JIAO Hong-mei;LI Shuang-ling;Lyu Ji-cheng;CUI Yi-min;ZHOU Ying;YANG Li;790-791
Efficacy and safety of different proprotein convertase subtilisin/kexin type 9 inhibitors in patients with hypercholesterolemia at high cardiovascular risk: a systematic review and meta-analysisMU Guang-yan;XIANG Qian;ZHOU Shuang;LIU Zhi-yan;QI Li-tong;JIANG Jie;GONG Yan-jun;XIE Qiu-fen;WANG Zi-ning;ZHANG Han-xu;HUO Yong;CUI Yi-min;791
Development of a novel prognostic signature based on antigen processing and presentation in patients with breast cancerQI Ao-shuang;ZHANG Qiang;ZHAO Lan;BI Jia;WEI Qian;JU Ming-yi;HE Miao;ZHAO Lin;WEI Min-jie;791-792
Associations between polymorphisms of endothelial nitric oxide synthase(eNOS) gene G298A, matrix metalloproteinase-3(MMP-3) gene 5A/6A, angiotensinogen(AGT) gene M235T,angiotensin Ⅱ type 1 receptor(AT1R) gene A1166C and risk of restenosis after percutaneoZHOU Shuang;WEI Shao-peng;LIU Zhi-yan;MU Guang-yan;WANG Zhe;XIANG Qian;CUI Yi-min;792
体医结合对老年前列腺增生症状的改善和生活质量的影响刘向云;陈廷;沈明康;793
替格瑞洛片在中国健康志愿者空腹和进食条件下的生物等效性研究谢秋芬;许俊羽;陈绩;何世英;赵侠;崔一民;793
临床药师对1例青霉素过敏的坏死性筋膜炎合并糖尿病患者的药学服务赵娜;史永志;解沛涛;肖斌;杜冠华;793-794专题报告和论文摘要_心血管药理学
TMEM16A在脑血管重构中血管平滑肌细胞迁移的作用机制郑华清;吕晓飞;关永源;794
类脑器官与移植治疗缪朝玉;794-795
尿素通道蛋白作为利尿和治疗高血压潜在药物靶点的确认和相关药物研发李飞;孙逸;李敏;任惠文;张顺;杨宝学;795
Puerarin inhibits hyperglycemia-induced NLRP3 inflammasome activation in endothelial cells via regulating autophagy processCAI Dong-peng;HAN Rui-fang;LIU Jia-ying;ZHENG Xin-yue;LIAN Da-wei;LAI Xiao-ping;CHEN Yang;795
Sodium ferulate inhibits cardiomyocyte hypertrophy induced by Ang Ⅱ through enhancement of NO/cGMP signaling pathwayCHEN Pan-pan;LUO Min;LU Yan-liu;JIN Feng;GONG Qi-hai;SHI Jing-shan;DENG Jiang;796
Inflammasome-independent NALP3 contributes to high-salt induced endothelial dysfunctionFU Hui;CHEN Ji-kuai;LU Wen-jie;JIANG Yu-jie;WANG Yuan-yuan;LI Dong-jie;SHEN Fu-ming;796-797
Roles of Zn2+ and mPTP in resveratrol-induced myocardial protection against endoplasmic reticulum stressHE Yi-fei;FU Yu;ZHAO Yang;LIU Yu-lin;XI Jin-kun;797
AMPK-ULK1 mediated autophagy contributed to myocardial injury by BCAA with a ROS independent pathwayJIANG Yu-jie;797-798
Identification of α-enolase phosphorylationsites at Ser268, Tyr270 and Thr272 involved in regulation of cardiomyocyte apoptosisLIANG Shu-miao;LU Jing;LIU Xue-ping;GAO Si;798
Cyclosporine, but not mycophenolate, increases nitric oxide products in mesenteric arteries of LDLR-/- miceMENG Mei;LI Zheng;LI Ting-ting;PM VANHOUTTE;SWS LEUNG;SHI Yi;799
Metrnl increases blood HDL-cholesterol and decreases blood triglycerideQI Qi;LI Zhi-yong;MIAO Chao-yu;799
Pathological upregulation of galectin-3 contributes to ischemia/reperfusion-induced cardiac dysfunctionTIAN Wen;MO Dan;QUAN Wei;ZHANG Hui-nan;SUN Yang;FENG Ying-da;HAO Xiao-wei;WANG Xue-ying;LIU Xiao-xiao;CAO Wei;LIU Wen-juan;LI Xiao-qiang;800
Salvianolic acid A protects H9C2 cardiomyocytes against hypoxia/reoxygenation injuryby regulating VDAC1WANG Dan-shu;YAN Liu-yan;WANG Rong-rong;WANG Shou-bao;FANG Lian-hua;DU Guan-hua;800-801
Carvedilol induces biased β1 adrenergic receptor-cGMP signaling in heartWANG Qing-tong;WEI Wei;XIANG K.Yang;801
Glycogen synthase kinase-3β inhibition alleviates NLRP3 inflammasome activation in myocardial infarctionWANG Shu-hui;XU Li-na;SU Xue-ling;MA Yu-ran;ZHANG Li-rong;HAN Sheng-na;801-802
LncRNA ACART protects cardiomyocytes from apoptosis by activating PPAR-γ/Bcl-2 pathwayWU Hao;ZHU Hai-xia;ZHUANG Yu-ting;ZHANG Ji-fan;DING-Xin;ZHAN Lin-feng;LUO Shen-jian;ZHANG Qi;SUN Fei;ZHANG Ming-yu;PAN Zhen-wei;LU Yan-jie;802
Circular RNA circ ASK1 acts as a microRNA-22 sponge to attenuate intimal hyperplasia by regulating TET2XIA Luo-xing;ZENG Zhi;QIN Jing-hong;LI Kang;TANG Wai-ho;802-803
Silencing of METTL3 attenuates cardiac fibrosis induced by myocardial infarction via inhibiting activation of cardiac fibroblastsXIE Yi-lin;ZHUANG Yu-ting;LI Ting-ting;SHANG Wen-di;JIANG Wen-mei;LI Chang-zhu;LI Ying;DONG Xue;WU Jia-xu;LU Yan-jie;PAN Zhen-wei;803-804
Endothelial Nlrp3 inflammasome activation is associated with endothelial function in mice fed a methionine choline-deficient dietYE Li-feng;ZUO Rui;WU Yan-jiao;Zhang Kai-min;ZHU Li;JIN Jia-qi;ZHANG Yang;CHEN Yang;804
Underlying mechanism of athycaltide-1, a novel peptide, ameliorating cardiac hypertrophy through down-regulation of CaMK ⅡZAHNG Jie;LI Jing-yuan;WANG Si-qi;ZHANG Yu-jia;TIAN Xin-miao;LIU Ying-yu;YU Jia-hui;XU Shu;LI He-xiao;HAO Li-ying;804-805
Aloe-emodin relieve Ang Ⅱ-induced endothelial junction dysfunction via Ang Ⅱ type 1 receptor-Nlrp3 ubiquitination pathwayZHANG Yi;ZHANG Kai-min;SONG Zi-qi;ZHU Li;JIN Jia-qi;CHEN Yang;805
Long noncoding RNAs: emerging players in cardiac electrical and structural remodelingZHANG Yong;ZHANG Ying;SUN Li-hua;YANG Bao-feng;805-806
AMPK-FOXO3a pathway inhibits fibroblast-myofibroblast differentiation by activating autophagy during pulmonary fibrosisZHENG Cheng;SI Rong;ZHANG Zhi-hui;QU Jiao;WANG Hua;GAO Jian;806
Role of a new-type polypeptide in regulation of oxidative stress in cardiac hypertrophy through ox-CaMK ⅡZHENG Xi;LI Jing-yuan;WANG Si-qi;ZHANG Chen-yang;HU Cong;TONG Xin;TIAN Xing;GU Li-xian;CHANG Xin-yi;HAO Li-ying;806-807
Inhibition of PKC represses the prolongation of QRS complex in EAM rat modelZHONG Chun-lian;JIA Lee;807
Cardio-protective effects of the new crystal of puerarin in isoproterenol-induced myocardial ischemia rats based on metabolomicsZHOU Yu-zhi;LI Meng-ru;SONG Jia;QIN Xue-mei;LYU Yang;DU Guan-hua;807-808
Responses of endothelial PP2Acα deficiency towards ischemic conditioning following ligation of the internal carotid arteryZHU Li;YANG Chen;808
新型Rho激酶抑制剂——DL0805-1通过抑制ROCK通路减轻肺动脉高压大鼠肺损伤及血管病变陈迪;袁天翊;陈俞材;王丹姝;孙姝婵;方莲花;杜冠华;809
心肌细胞缺氧复氧模型的建立方法及能量代谢相关检测指标研究进展陈雨;李艳;王玮玮;姜丽;809
硫化氢在抗动脉粥样硬化的研究进展董秋红;周春阳;809
缬沙坦通过GJA1-20k促进缝隙连接形成逆转心肌肥厚付一乐;陶亮;王琴;809-810
细胞内外sFRP1对多柔比星心肌病的不同作用及机制胡粤怀;路静;蒋建敏;刘培庆;810
免疫系统异常在孕期炎症刺激致子代动脉粥样硬化发生的作用及机制季妍;邓有才;李晓辉;810
长链非编码RNA-ZFAS1通过诱发心脏钙超载诱导心肌梗死模型小鼠心肌细胞凋亡焦磊;810-811
蛭芎胶囊工艺变更前后对脑动脉硬化模型大鼠的影响李佳;刘聪;吴鑫平;郝旭亮;811
高脂血症与动脉粥样硬化和脂代谢研究进展李文毅;周春阳;811
心脏脂肪酸代谢抑制在孕期炎症刺激致子代小鼠心脏损伤中的作用及机制宋亮;邓有才;李晓辉;812
晶Ⅴ型葛根素对心肌缺血小鼠的药效学研究孙姝婵;方莲花;吕扬;杜冠华;812
淫羊藿苷通过调节巨噬细胞极化抑制肺动脉高压血管重构唐超;黄波;徐尚福;罗云梅;李沙;李利生;812
肺动脉高压治疗药物研究进展谢焕章;贾力;812-813
GSK-3β抑制剂下调大鼠心肌梗死后CD47表达的升高徐丽娜;苏雪灵;王淑慧;韩圣娜;813
共晶物DL1602改善异丙肾上腺素致心衰大鼠心功能的实验研究燕柳艳;王守宝;杜冠华;813
低氧诱导小鼠肺动脉高压模型的建立袁天翊;陈迪;孙姝婵;方莲花;杜冠华;813-814
慢性肾衰高磷血症诱导的血管钙化与心血管疾病的相关性及防治进展赵璐璐;邢海燕;王胜男;高原;谷超;李刚;814专题报告和论文摘要_药物代谢
基因编辑技术创新构建大鼠药物代谢模型及其应用王昕;814
Systematic external evaluation of published population pharmacokinetic models of tacrolimus in adult liver transplant recipientsCAI Xiao-jun;LI Rui-dong;SHENG Chang-cheng;TAO Yi-feng;ZHANG Quan-bao;ZHANG Xiao-fei;LI juan;SHEN Cong-huan;QIU Xiao-yan;WANG Zheng-xin;JIAO Zheng;814-815
Metabolomics study of Shenfu Injection on mid-stage cardiogenic shock rats by UPLC-Q-TOF/MSJIANG Li;LI Bing-tao;ZHANG Qi-yun;CHEN Yu;WANG Wei-wei;XU Guo-liang;815
Evaluation of assays for aminoglycosides in serum:a comparison of accuracy and precision based on external quality assessmentLI Meng-ya;CHEN Chao-yang;LEI Li-li;Zhao Xia;ZHOU Ying;CUI Yi-min;815-816
Involving nonlinear kinetics to improve predictive performance of population pharmacokinetic models for cyclosporine in adult renal transplant recipients: a comparison of modelling strategiesMAO Jun-jun;JIAO Zheng;QIU Xiao-yan;ZHONG Ming-kang;816
No effect of acylpeptide hydrolase polymorphisms on pharmacokinetics of sodium valproate in healthy Chinese male volunteersWEN Zhi-peng;Zeng Wen-jing;XIAO Jian;CHEN Xiao-ping;816-817
Population pharmacokinetic modeling for mycophenolic acid and its main glucuronide metabolite in Chinese kidney transplant recipientsYANG Chun-lan;SHENG Chang-cheng;FENG Li-juan;JIAO Zheng;XU Du-juan;817
Metabolomics combined with serum pharmacochemistry discovering effective compounds of Fangji Huangqi Tang against nephrotic syndromeYANG Liu;LI Ai-ping;CUI Wen-bo;QIN Xue-mei;817-818
A CYP716A enzyme function of oleanane oxidase in biosynthesis of triterpenoid in Polygala tenuifolia willdZHANG Fu-sheng;MEI Yue-ju;WANG Qian-yu;PU Ya-jie;DU Chen-hui;QIN Xue-mei;TIAN Hong-ling;LIAN Yun-lan;LI Min-sheng;CHEN Yu;MA Cun-gen;818
Effect of Chinese herb Danzhi Xiaoyao pills on pharmacokinetics of venlafaxine in beaglesZHU Yong-liang;LI Shuang-long;WU Meng-yuan;QIU Xiang-jun;818-819
lncRNA HNF4α-AS1参与调控转录因子和细胞色素CYP450表达陈施彤;王以婷;常琦;张莉蓉;819
甘草酸二铵调节CYP450酶和血浆蛋白结合率对奥美拉唑药代动力学的影响韩璐;王蓉;吴斌;顾妍秋;原永芳;819-820
UHPLC-MS/MS法测定大鼠血浆中黄芪建中汤13种成分浓度贾璐;刘月涛;秦雪梅;820
HPLC-DAD/MS法测定辛伐他汀滴丸储存中有关物质含量变化孔德文;宋俊科;赵晓悦;梁宇;周启蒙;820
基于LC-MS代谢组学的注射用黄芪多糖活性成分对巨噬细胞吞噬活性的影响李树颖;李科;秦雪梅;李先荣;杜昱光;820
蓓萨罗丁固体分散体制备及药物代谢动力学检测任淑月;焦凌泰;于浩滢;王景蓉;宋俊科;杨世颖;吕扬;孙岚;杜冠华;821
伊立替康不良反应与UGT1A1基因多态性和血药浓度关系的研究任帅;刘晓明;821
DNA甲基化参与PXR介导的CYP3A4的表达王晓飞;魏璐嫚;王以婷;陈师彤;孟祥光;张莉蓉;821-822
平衡透析法结合LC-MS/MS研究奥克梯隆型皂苷元的大鼠血浆蛋白结合率燕晓晶;李振国;姜杰;英子越;耿聪;822
茵陈术附汤挥发性成分在大鼠体内药代动力学研究昝斌;王天明;李园园;石荣;马越鸣;822
UPLC-MS-MS测定来自中药九里香中九里香酮的血药浓度翟胜益;江舟;张晨;贾力;822-823
多种DL1801共晶化合物的大鼠体内药代动力学研究赵晓悦;曹俊姿;王海港;宋俊科;梁宇;杜冠华;823专题报告和论文摘要_教学与科普
来华留学临床医学教育面临的问题及对策张岫美;823-824
药理学金课建设王艳春;范红艳;张丽红;来永巍;马赫;康晶;王春晓;安英;任旷;824
失眠机制及药物治疗曲卫敏;黄志力;824
静脉滴注并不“快”曹永孝;824
团队自主学习模式在中药药理学教学中的应用方芳;825专题报告和论文摘要_肾脏药理学
肾脏中G蛋白偶联受体信号转导的多样性孙金鹏;825
线粒体:急性肾损伤治疗的新靶标张爱华;825
FOXO1 inhibition prevents renal ischemia-reperfusion injury via promotion of CREB/PGC-1α-mediated mitochondrial biogenesisWANG Di;LIU Qian;LI Xue-jun;TIE Lu;826
Petroleum ether extract of Derris eriocarpa How.(PEEDEH) investigate antidiabetic nephropathy effect and mechanism through TLR4/NF-κB/caspase-3 pathwaysYANG Li-fang;DENG Li-yao;WEI Yan-ye;GAO Cai-mi;XIA Yu-hong;JIANG Ming-guo;826-827
Contribution of TFEB-mediated autophagy totubulointerstitial fibrosis in mice with adenine-induced chronic kidney diseaseYUAN Hui-qi;YE Li-feng;ZUO Rui;JIN Jia-qi;CHEN Yang;827
Morin reduce uric acid level in hyperuricemia miceZHOU Qi-meng;ZHAO Xiao-yue;YANG Hai-guang;WANG Hai-gang;LIANG Yu;KONG De-wen;ZAHNG Sen;ZHANG Wen;SONG Jun-ke;DU Guan-hua;827
姜黄素对TNF-α诱导人肾小球系膜细胞增殖及PTX3表达的作用研究杜世豪;冀凯;李新;谢群玲;徐浩;刘中信;郑涛;王亚越;范华英;827-828
endophilin A2抑制小鼠肾间质纤维化的形成麦晓仪;周家国;张敏州;828
圆锥绣球提取物治疗慢性肾功能不全的临床前开发及药理机制王伟达;李昭君;马洁;盛莉;张东明;陈晓光;张森;828-829专题报告和论文摘要_民族药物生化与分子机制
冠心活血胶囊的药效学研究常福厚;829
Pharmacological and toxicological studies of famous Chinese medicine Hua-Feng-DanZHANG Feng;XU Shang-fu;LI Li-sheng;LIU Jie;SHI Jing-shan;829
Melanin homeostasis plays an important role in kaempferide-induced melanogenesisYU Lan;SONG Zong-qiang;LI Tian-yi;DING Qiong;LUO Lin;CHEN Han-ying;WANG Xiao-qin;ZHANG Bo;829-830
Physcion and physcion 8-O-β-glucopyranoside:a review of their pharmacology, toxicities and pharmacokineticsLI Xun;LIU Ying-jiao;CHU Shi-feng;YANG Song-wei;PENG Ye;REN Si-yu;WEN Bi-rui;CHEN Nai-hong;830
人参皂苷抗氧化应激损伤作用及其作用机制的研究进展陈德云;李发靖;陈鹏;杨仁华;赵殊红;张瑞;沈志强;何波;830-831
EGCG的药理作用及作用机制矫林池;姚维凡;钟欣;杜可;刘明妍;831
基于网络药理学探讨蒙药锁阳促智作用的物质基础李丹;韩瑞兰;赵雪;郝云雪;831
拟黑多刺蚁活性组分药理作用研究进展李冬梅;韦桂宁;831
人参皂苷对细胞自噬信号通路调控作用的研究进展李发靖;陈德云;陈鹏;杨仁华;姜发坤;张瑞;何波;沈志强;831-832
鹿茸胶原酶解物对地塞米松诱导成骨细胞MC3T3-E1凋亡的保护作用李娜;王继凤;兰兴成;陈锡俊;李辉;杨擎;曲晓波;832
紫花地丁烫伤酊治疗大鼠烫伤模型试验刘擎;陈依春;李捷;郝婷婷;周自强;孙芳云;832
蒙药朱日很滴丸对急性心肌缺血的影响王芳;常福厚;肖云峰;刘静;张谦;832
基于网络药理学和生物信息学分析桂枝茯苓丸治疗多囊卵巢综合征的作用机制于莹;张功;韩涛;黄海量;832-833
基于“活性成分-作用靶点-通路”网络葛根抗缺氧作用生物机制研究翟兴英;李冰涛;李佳;曹浩时;江文俊;徐国良;朱卫丰;刘荣华;833
蒙药毒性效应及影响因素张谦;李君;刘静;常福厚;833
金钗石斛生物碱对四氯化碳所致小鼠肝线粒体损伤的保护作用及机制周金鑫;张娅;周少玉;石富国;石京山;刘杰;吴芹;833-834专题报告和论文摘要_综合交叉药理学
Identification of two natural coumarin enantiomers for selective inhibition of heat-activated TRPV2 channelsZHOU Qi-qi;SHI Yun-tao;QI Hang;LIU Hui-jie;WEI Ning-ning;JIANG Yong;WANG Ke-wei;834
小鼠应激易感与耐受模型的建立楚沙沙;石天尧;周文霞;834
基于多学科的靶标发现和确证党永军;835
放射性肺纤维化基质重构与肌成纤维细胞凋亡抵抗的相关性郭凯宁;陈金燃;陈张杰;郑建星;洪金省;陈纯;835
药物毒理学的研究进展韩运祺;肖云峰;钱新宇;王娜;835
植物中有机硫化物的提取分离工艺研究进展黄蓉;廖一臣;赖能;周春阳;835-836
小鼠骨骼肌表型和性别对饥饿诱导肌肉因子FNDC5表达的影响贾伟华;王诺琦;殷琳;李娜;陈熙;侯碧玉;强桂芬;杨秀颖;杜冠华;836
疽愈喷剂对骨髓炎模型兔骨修复中ADAMTS-7和骨Ⅰ型胶原表达的机制研究李鼎鹏;谢兴文;潘兴戊;徐世红;许伟;836
苦苣菜药材细粉混悬液安全药理学研究李君;常福厚;胡玉霞;王敏杰;白图雅;张梦迪;836-837
精子优选新方法建立及相关调节机制研究李坤;孙培蓓;李瑞;郑东旺;王雅艳;倪崖;837
NLRP3炎性小体介导曲妥珠单抗增强多柔比星所致心脏毒性的作用李文群;李元建;李晓晖;向大雄;张毕奎;837
丹酚酸A联合低剂量泼尼松对多柔比星诱导的微小病变型肾病的保护作用研究李新;冀凯;杜世豪;王学凯;王梦影;刘彦君;范华英;837-838
药物依赖性试验方法概述刘静;张谦;张微;肖云峰;王芳;李君;常福厚;838
分子药理学研究进展钱新宇;肖云峰;王娜;韩运棋;838
人精子中Slo1和Slo3钾离子通道共同参与调控精子获能过程孙培蓓;李坤;郑东旺;王雅艳;倪崖;838-839
山萘酚通过抑制伽马辐射诱导的氧化应激和凋亡发生来发挥辐射防护作用王静;839
我国新药研发的研究进展王娜;常福厚;钱新宇;韩运祺;839
急性应激障碍向创伤后应激障碍转化模型的建立王子元;王昊;黄晏;周文霞;张永祥;839-840
甘草酸防治雷公藤肝毒性的研究进展文苾蕊;张志玲;陈乃宏;840
新药研发过程中的毒理学肖云峰;常福厚;钱新宇;王娜;韩运祺;840
LW-AFC对60Co射线辐射损伤小鼠预防作用的初步研究周中林;尉明晓;郭丽萍;楚沙沙;石天尧;周文霞;840
新型避孕药的研究进展及其非避孕益处的应用进展朱焰;840-841专题报告和论文摘要_神经药理学
Effect of active components group of Xiaoxuming decoction on cerebral mitophagy after focal cerebral ischemia/reperfusion injuryBAI Xue;DU Xiao;HE Xiao-li;841-842
Orexinergic neurons lesion partially prevent hypertension and sleep disturbance in spontaneously hypertensive ratsCUI Su-ying;HUANG Yuan-li;CUI Xiang-yu;ZHAO Hui-ling;HU Xiao;LIU Yu-tong;QIN Yu;Nurhumar KURBAN;ZHANG Yong-he;842
Pharmacological effects of Rg1 in neuropsychopharmacologyGAO Yan;CHU Shi-feng;ZHANG Zhao;ZHANG Lan;CHEN Nai-hong;842-843
Andrographolide alleviates parkinsonism in MPTP-PD mice via targeting DRP1-mediated mitochondrial fissionGENG Ji;LIU Wen;XU Qiang;GUO Wen-jie;GAO Jing;843
Tetramethylpyrazine nitrone improved mitochondrial dysfunction, downregulated α-synuclein, and reduced neurodegeneration in Parkinson disease modelsGUO Bao-jian;ZHENG Cheng-you;QIU Xiao-ling;ZHANG Zai-jun;843-844
Effect of active ingredient of Stephaniajaponica(Thunb.) Mierson lipopolysaccharide-induced activation of microgliaHAO Ting-yu;YANG Yan-qiu;XU Ji-kai;LIU Jing-yu;CHE Yue;LI Ning;HOU Yue;844-845
Balance of synaptic and extrasynaptic NMDA receptors play an important role in beta-amyloid induced neurotoxicityHUANG Yan;SHEN Wei;LIU Gang;ZHANG Yong-Xiang;ZHOU Wen-Xia;845
Cornin protects astrocytes against autophagy induced by cerebral ischemia-reperfusion via PI3K/Akt/mTOR pathwayLAN Tian-chi;XU Yang-yang;LI Shu-cui;LIU Hui;ZHU Hai-bo;ZHANG Shu-ping;845-846
Effects of GBEE on memory impairment induced by scopolamine in mice and activity of AChE in cerebral cortexLUO Cheng-rong;WANG Meng-meng;CHEN Jing-ru;MAO Lei-lei;XU Ai-hua;846-847
Ethanol induces sedation and hypnosis via inhibiting histamine release in miceMA Zhang-qing;WANG Wu-san;WANG Tian-xiao;XU Wei;QU Wei-ming;HUANG Zhi-li;HONG Zong-yuan;847
Ethanol increases GABA release in tuberomammillary nucleus but not in frontal cortex in ratsMA Zhang-qing;WANG Wu-san;HUANG Zhi-li;HONG Zong-yuan;848
Increased blood pressure variability induces depression-like behavior and gap junction protein changes in ratsMIAO Shen;ZHOU Li-jun;TAN Rui;ZHANG Fang-fang;GAO Shan;ZHOU Yan-meng;HOU Xue-qin;JI Wei;ZHU De-rong;ZHANG Han-ting;ZHAO Xiao-min;848
Research advances in treatment of Alzheimer disease with traditional Chinese medicines for invigorating kidney and removing phlegmNING Fu-nan;SHI Kun;XIE Guang-jing;LAN Zhou;WANG Ping;848-849
Anti-aging effect of aqueous extract from Astragalus membranaceus on Drosophila melanogasterQIAO Yu-qi;ZHANG Jian-qin;QIN Xue-mei;849
Cerebral organoids repair ischemic stroke brain injuryWANG Shu-na;WANG Zhi;XU Tian-ying;CHENG Ming-he;LI Wen-lin;MIAO Chao-yu;849-850
Mitochondrial dysfunction and neuroinflammation in Parkinson diseaseWANG Yu-xi;ZHANG Si-ran;ZHOU Jun-yu;ZHAO Jian-bo;LI Cheng-tan;ZHANG Li-hui;850-851
Syntaxin 17 inhibits ischemic neuronal injury by enhancing autophagy flux and reducing endoplasmic reticulum stressXIA Yun-fei;CHEN Lei;SHEN Shu-fang;CHEN Jia-li;QIAN Ke;CHEN Zhong;QIN Zheng-hong;SHENG Rui;851
PDE7A expression on alcohol consumption and alcohol withdrawal in striatum of C57BL/6J miceXU Bing-bing;ZHOU Yan-meng;ZHANG Han-ting;851-852
Effect of α-asarone on ethanol-induced learning and memory impairment in mice and its underlying mechanismXU Fei-fei;LI Qin-qing;ZHANG Qi;LI Xiao-qing;GUO Mei-tong;ZHANG Yi-ming;WANG Zi-lin;WANG Jie;ZHAO Jia-qi;TIAN Ya-juan;ZHANG Zhao;CHU Shi-feng;HE Wen-bin;852
Effect of ostholon memory and tau protein phosphorylation in brain of AD miceXU Li;HOU Xue-qin;852-853
P7C3-A20 is not a direct Nampt activatorXU Tian-ying;ZHANG Sai-long;WANG Shu-na;WANG Xia;MIAO Chao-yu;853
Baicalein attenuates neuroinflammation in LPS-activated BV-2 microglial cells through suppression of pro-inflammatory cytokines,COX2/NF-κB expressions and regulation of metabolic disorderYAN Jiao-jiao;GAO Li;QIN Xue-mei;854
Attenuation of cerebral ischemia-reperfusion injury by specific activation of Kv7/KCNQ/MchannelsYANG Pan;LIU Ya-ni;WANG Ke-wei;854-855
Drug-target interaction prediction with deep learningYANG Shuo;LI Shi-liang;LI Hong-lin;855
Functions of connexin-43 in neural development and its relationship with neural diseasesYANG Xiong;CHU Shi-feng;CHEN Nai-hong;855
Development of sensitive mass spectrometry methods for qualitative and quantitative studies on active components of Xiaoxuming decoction, a traditional Chinese medicine prescription for ischemic strokeYANG Zhi-hong;LUO Xiao-ya;CHEN Xi-rui;SHEN Xiao-ling;LIU Ye-ju;DU Guan-hua;855-856
PPARβ/δ-agonist F3SM and GW501516 ameliorates dysfunction in glycolysis in sAD patient iPSCs derived neural stem cellsZHANG Lin;REN Qiao;JIANG Ning;ZHOU Wen-xia;ZHANG Yong-xiang;856
Improving effect and mechanism of fisetin on cell model of diabetic cerebral microangiopathyZHANG Yi-ming;WANG Jie;XU Fei-fei;LI Xiao-qing;GUO Mei-tong;WANG Zi-lin;TIAN Ya-juan;LI Qin-qing;CHU Shi-feng;HE Wen-bin;856-857
Computational systems pharmacology reveals anantiplatelet and neuroprotective mechanism of Deng-Zhan-Xi-Xin injection in treatment of ischemic strokeZHAO Jing;LYU Chao;WU Qiu-ling;ZENG Hua-wu;GUO Xin;YANG Jian;TIAN Sai-sai;ZHANG Wei-dong;857-858
Role of serotonin signaling in depression-like behavior induced by increased blood pressure variability in ratsZHOU Li-jun;MIAO Shen;TAN Rui;ZHANG Fang-fang;ZHU De-rong;JI Wei;GAO Shan;HOU Xue-qin;ZHOU Yan-meng;ZHAO Xiao-min;858
Matrilin-3 is found in brain and promotes brain functional recovery in rats ischemic stroke via targeting astrocytesZHOU Xian-yong;ZHU Yong-ming;ZHANG Hui-ling;858-859
Syb-pr Ⅱ对三叉神经痛大鼠的镇痛作用研究及机制研究班梦祺;曹义;宋永波;吴春福;李春莉;859
姜黄素类似物Cur20的抗痴呆作用岑娟;张润芳;陈梦莹;郑贝贝;张峰;859
δ阿片受体转激活EGFR发挥神经保护作用的机制研究陈玫璇;武烁;王烈成;张乐莎;859-860
Rg1和Rb1治疗缺血性卒中的研究进展崔丽媛;楚世峰;陈乃宏;860
三萜类化合物的神经药理作用董一筱;张钊;陈乃宏;860
富含脯氨酸的酪氨酸激酶2与突触可塑性杜雨生;张钊;何新;860
岛叶皮质在观察性恐惧习得中的作用郭丽萍;石天尧;周文霞;860-861
α-突触核蛋白对帕金森病自我免疫病理的影响韩奇文;苑玉和;陈乃宏;861
CKLF1在缺血性卒中中的作用研究进展何宏媛;楚世峰;陈乃宏;861
降钙素基因相关肽在神经性痛大鼠扣带回内的痛觉调节作用及其机制侯可赛;傅风华;于龙川;861-862
补阳还五汤治疗神经退行性疾病作用机制研究进展胡耀梅;刘芳;刘应蛟;艾启迪;陈乃宏;862
孕期地塞米松暴露所致雌性子代大鼠海马谷氨酸能系统和神经行为改变黄松强;汪晖;徐丹;862
阿尔茨海默病临床治疗策略的研究进展李高;贾力;862
罗替戈汀缓释微球对炎症性疼痛的镇痛作用李婷;王琳琳;傅风华;刘荣霞;王天;862-863
Ⅰ型大麻素受体调控焦亡通路介导抗精神病药心肌毒性的机制李小青;王婧;林馨怡;李立亮;863
N-酰基乙醇胺酸性水解酶(NAAA)促进脑皮质挫伤(TBI)中血脑屏障的破坏李宇航;863
百可利对鱼藤酮损伤模型小鼠自噬的影响梁宇;赵晓悦;孔德文;周启蒙;张森;杜冠华;863-864
丹酚酸A与阿司匹林预防给药对血脑屏障保护作用的比较刘成娣;刘楠楠;孔令雷;杜冠华;864
小胶质细胞极化在帕金森病中的作用刘家岐;楚世峰;张大永;陈乃宏;864
水通道蛋白4参与抑郁症发病机制研究进展刘诺;王真真;陈乃宏;864
线粒体能量代谢障碍在抑郁症发病机制中的关键作用刘少博;令狐婷;高耀;田俊生;秦雪梅;865
5-脂氧酶及其抑制剂在MPP~+诱导PC12细胞损伤中的作用刘婷;王羽茜;严梦蝶;王艳芳;李成檀;张丽慧;865
EGCG通过调控胱天蛋白酶介导的NLRP3炎症小体激活抑制LPS+Aβ诱导BV2细胞的炎症反应刘洋;钟欣;刘明妍;魏敏杰;865
星形胶质细胞-神经元的相关关系研究进展刘应蛟;胡耀梅;李洵;彭也;楚世峰;陈乃宏;865-866
单次皮质酮注射对小鼠情绪症状与认知功能的影响路畅;王陈;黄晏;周文霞;张永祥;866
灵芝酸对小鼠局灶性脑缺血再灌注损伤的保护作用及机制研究马昂;全亚竹;邵广莹;耿晓强;林树钱;杨宝学;866
药物CIG调节tau蛋白磷酸化改善转基因小鼠的tau蛋白病变马登磊;罗艺;李林;张兰;866-867
人参中有效成分对脑缺血再灌注损伤保护作用的研究进展彭也;张钊;陈乃宏;867
人诱导性多能干细胞源性小胶质细胞诱导方法的建立及其表型和功能的初步研究任巧;张林;蒋宁;周文霞;867
FAAH/MAGL抑制剂在中枢神经系统疾病治疗中的潜在应用任思宇;王真真;陈乃宏;867-868
百可利防治多发性硬化症的作用及机制申艳佳;杨冉;陈渺;李莉;杜冠华;868
丹酚酸A通过激活Nrf2抗氧化通路同时抑制MMP-9保护血脑屏障共同发挥抗脑缺血再灌注损伤作用宋俊科;杜冠华;868
星形胶质细胞与神经退行性疾病的相关性苏晓梅;张丹参;868-869
芳香烃受体对皮质酮致LTP损伤作用影响的初步研究孙娜;王陈;黄晏;周文霞;张永祥;869
星形胶质细胞焦亡与抑郁症发生的相关性孙一鸣;张青玉;李雪婷;贺章;丁建花;鲁明;胡刚;869
激动NMDA受体甘氨酸位点可改善皮质酮致海马长时程增强损伤王陈;黄晏;周文霞;张永祥;869-870
脑缺血再灌注神经细胞凋亡机制研究进展王冬睿;范蕾;870
mTOR信号通路介导姜黄素抗抑郁作用机制王金梦;杨玉;陈春林;870
靶向垂体库欣病药物治疗研究进展王景蓉;于浩滢;任淑月;孙岚;杜冠华;870
降钙素基因相关肽在大鼠臂旁核内痛觉调节作用的研究王琳琳;傅风华;于龙川;871
缺血性卒中患者基因表达谱的生物信息学分析王蓉蓉;王丹姝;燕柳艳;姜瑜;王守宝;杜冠华;871
咔唑类生物碱衍生物CZ-7对cuprizone诱导的动物模型髓鞘再生的影响及机制王莎莎;张钊;陈乃宏;871
大株红景天胶囊对小鼠抗疲劳作用研究王艺博;肖智勇;周文霞;张永祥;871-872
类脑救治脑创伤的研究王治;王淑娜;徐添颖;缪朝玉;872
急性应激对背、腹侧海马成年神经再生的影响尉明晓;石天尧;张永祥;周文霞;872
毛蕊花糖苷促进神经递质释放的分子机制邢海燕;王胜男;赵璐璐;高原;谷超;李刚;872-873
柴归颗粒对抑郁模型大鼠行为学及HPA轴的影响许腾;赵映霞;高耀;田俊生;秦雪梅;873
代谢组学结合网络药理学技术探讨黄芪-丹参药对预防大鼠脑缺血的药效机制薛倩倩;刘月涛;秦雪梅;873
MYR通过NF-κκB信号通路改善LPS诱导小鼠纹状体炎症反应杨滢霖;刘漫;程笑;李伟翰;张姗姗;王月华;杜冠华;873-874
低剂量氯胺酮联用丁苯酞对急性抑郁小鼠行为的影响杨玉;王金梦;陈春林;874
醒脑静注射液对脑出血小鼠神经功能的影响杨韵琦;岳淑敏;范艺千;马征;王天;傅风华;874
SZY改善氧化应激致认知障碍的作用于蕾;贺晓丽;874-875
NMDA受体在皮质酮介导海马突触可塑性损伤中的作用于琪;黄晏;周文霞;张永祥;875
卒中后中枢疼痛的机制研究进展詹佳虹;楚世峰;陈乃宏;875
基于全球上市药物数据的抗阿尔茨海默病重定位新药发现张宝月;贾皓;王喆;刘艾林;杜冠华;875-876
小柴胡汤对围绝经期小鼠抑郁焦虑症状的改善作用及其机制张阔;王芷倩;杨静玉;吴春福;876
exendin-4对Aβ介导的星形胶质细胞炎症反应的改善作用及与NLRP2相关通路的研究张孟俊;谢韫祯;陈瑞瑜;周宇;陈洲;876
中药多糖治疗神经退行性疾病及其机制张瑞娟;景永帅;张丹参;876-877
银杏内酯通过激活Nrf2和CREB核转位促进抗氧化和抗凋亡基因表达发挥抗脑缺血再灌注损伤作用张雯;杜冠华;877
植物雌激素抑制线粒体途径凋亡发挥神经保护作用的机制甄艳杰;郭童林;沈丽霞;877
黄芪甲苷的神经保护作用研究进展郑清炼;楚世峰;许鑫;陈乃宏;877
帕金森病的病因学周甜甜;苑玉和;陈乃宏;877-878
趋化因子介导脑缺血后神经修复的研究进展周欣;楚世峰;陈乃宏;878
PPARα促进自噬流抑制脑缺血后星形胶质细胞的过度激活周宇;罗豆豆;叶文选;员晓倩;张亚莉;潘毅林;金鑫;878
星形胶质细胞多巴胺D2受体通过β-arrestin 2偏爱型通路调控神经炎症朱佳蕾;周琰;杜仁红;鲁明;胡刚;878-879专题报告和论文摘要_肿瘤药理学
Up-regulation of Cx43 expression in exosomessecreted by glioblastoma under hypoxia promotes proliferation of HUVECsBI Qiu-chen;ZHANG Le-ling;GAN Li-jun;TAN Ren-jie;LAN Xue-mei;HONG Tao;LIU Rong;QIU Cheng-lin;HAN Xiao-jian;JIANG Li-ping;879
Denosumab versus zoledronic acid in prevention of skeletal-related events in vulnerable cancer patients:a meta-analysis of randomized controlled trialsCHEN Chao-yang;LI Ruo-ming;YANG Ting;MA Ling-yun;ZHOU Shuang;LI Min;ZHOU Ying;CUI Yi-min;879-880
Both IDO1 and TDO contribute to malignancy of gliomas via Kyn-AhR-AQP4 signal pathwayDU Li-sha;XING Zi-kang;TAO Bang-bao;LI Tian-qi;YANG Dan;LI Wei-rui;ZHENG Yuan-ting;KUANG Chun-xiang;YANG Qing;880
Description of circRNA-associated-ceRNA networks and potential role of circANKRD12 in ovarian cancer cellsGUAN Qiu-tong;JIANG Long-yang;ZHANG Ming;WEI Qian;HE Miao;BI Jia;WEI Min-jie;ZHAO Lin;880-881
Mechanisms of migration and invasion promoted by NSCLC cells-derived exosomesGUO Qiao-ru;HUANG Wen-jing;YAN Yan-yan;LIU Yun;LIN Min-ting;LI Jia-jun;SU Chao-yue;ZHANG Jian-ye;881
Mechanism of anti-breast cancer compound produced by marine fungusHONG Kui;881-882
Sambutoxin sensitizes K562/ADR to adrimycin by inhibiting expression of P-glycoproteinLI Xiao-tong;SHI Zhao-yu;LI Ying-shang;ZHAO lin;GUO Xiu-li;882
Advanced therapies on BRAF-mutated and KRAS-mutated metastatic colorectal cancerLI Zi-nan;YU Li-feng;WANG Jia-qi;NIU Yan-xin;WANG Xin-yu;ZHAO Lin;883
BCL6 inhibition sensitizes solid tumors to TopoⅡ inhibitorsLIU Ya-nan;PANG Xiu-feng;883
LL1, a novel specific STAT3 inhibitor, displays anti-colorectal cancer activities in vitro and in vivoLIU Zhe;WANG Huan;GUAN Ling-nan;LAI Chong;YU Wen-ying;LAI Mao-de;884
Ginkgo biloba exocarp extracts inhibits metastasis and its effects on TGF-β1/ERK1/2/MMP-9 signaling pathway in B16-F10 melanomaLUO Cheng-rong;WANG Meng-meng;GAO Yan-qi;CHEN Hua-sheng;XU Ai-hua;884-885
Mitomycin C synergizes with PD-L1 blockade in treatment of non-small cell lung cancerLUO Min;ZHANG Hong;WU Shao-cong;CHEN Zhen;LIANG Shao-bo;WANG Fang;FU Li-wu;885
Cryptotanshinone switches target from estrogen receptor α to breast cancer resistance protein(BCRP/ABCG2) to reverse multidrug resistance in breast cancerNI Wen-ting;FAN Hui;YU Su-yun;CHEN Wen-xing;LU Yin;885-886
Isoliquiritigenin derivative inhibits tumor initiation and progression through modulating miR-374a/BAX/caspase-9 axis in triple negative breast cancerPENG Fu;XIONG Liang;886
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitinationREN Ying;XU Xin;MAO Chen-Yu;HAN Kun-Kun;XU Yu-Jia;CAO Bi-Yin;ZHANG Zu-Bin;SETHI Gautam;TANG Xiao-Wen;MAO Xin-Liang;886-887
Impact of immune infiltration on tumor development and progressionWANG Lin;LI Xue-ping;SONG Xin-yue;BI Jia;WEI Min-jie;ZHAO Lin;887
2-DG regain sensitivity of drug resistant colon cancer on 5-FU via blocking LKB1/Nrf2/Stat3 mediated metabolic reprogrammingWANG Lin;YU Zi-ru;WANG Rui;DU Guan-hua;887-888
Prospect of combination of anti-PD-1/PD-L1 therapy and other therapeutics for treatment of lung cancerWANG Lu-yao;YAO Rui-xue;XU Qian-qian;LIU Jia;888
Panaxadiol inhibits programmed cell deathligand 1 expression and tumor proliferation via hypoxia-inducible factor(HIF)-1a and STAT3 in human colon cancer cellsWANG Zhe;LI Ming-yue;ZHANG Zhi-hong;MA Juan;JIN Xue-jun;888-889
Functional studies of matrine as an agent targeting tumors harboring IDH1/2 mutationsWU Xing-kang;LU Yu-fang;ZHANG Meng-chen;QIN Xue-mei;889
Antiphospholipid autoantibodies promote breast tumor progression by tissue factor-dependent vascular normalizationWU Yuan-yuan;NGUYEN ANDrew;WU Xiao-xuan;RAND Jacob;LINE laine;LU Yin;889-890
A network-based predictive gene expression signature for recurrence risks in stage Ⅱ colorectal cancerYANG Wen-jing;WANG Hai-bo;WANG Wen-da;ZHANG Gan-lin;YANG Guo-wang;890
2-phenyl-3,4-thiadiazole [3,2-α]-pyrimidine-7-one inhibits cell proliferation by changing the cell cycle and inducing endogenous and exogenous apoptosis in HeLa cellsYANY Yan;WANG Min-jie;BAI Tu-ya;LYU Xiao-li;FAN Lei;CHANG Fu-hou;890-891
Daphne-type diterpenes from Daphne linn and their anti-tumor activityYAO Guo-dong;HOU Zi-lin;SHANG Xin-yue;SONG Shao-jiang;891
Rociletinib(CO-1686) enhanced efficacy of chemotherapeutic agents in ABCG2-overexpressing cancer cells in vitro and in vivoZENG Fan-pu;WANG Fang;ZHENG Zong-heng;CHEN Zhen;Kenneth Kin Wah To;ZHANG Hong;HAN Qian;FU Li-wu;891-892
Aberrant FoxM1 expression increases ASPM transcription and promotes progression of gliomasZENG Wen-jing;WEN Zhi-peng;GONG Zhi-cheng;CHEN Xiao-ping;892
Identification of novel epithelial-mesenchymal transition-related gene features to predict survival outcome in patients with pancreatic cancerZHANG Qiang;JIANG Long-yang;LI Xue-ping;YUAN Guan-li;GUAN Qiu-tong;QI Ao-shuang;SONG Xin-yue Song;JIA Zhen;ZHAO Lin;WEI Min-jie;892-893
Convallatoxin promotes apoptosis and inhibits proliferation through crosstalk between JAK2/STAT3(T705) and mTOR/STAT3(S727) signaling pathwaysZHANG Zhi-hong;LI Ming-yue;WANG Zhe;JIN Hong-lan;MA Juan;JIN Xue-jun;893-894
Anti-tumor and reversing MDR effects of conglobatin a macrolide dilactone compoundZHANG Zi-qiang;LIU Ling-xue;MA Chun-ling;XU Jian-hua;894
Esterified derivate of sinomenine exerts inhibitory effect on glioblastomaZHENG Xiang-jin;REN Li-wen;LIU Jin-yi;TANG-Qin;DU Guan-hua;WANG Jin-hua;894
Overlapping and uniqueroles played by ROCK1 and 2 in modulation of coding and long noncoding RNA expressionZHOU He-ming;ZHANG Ji-gang;ZHANG Xue;FAN Guo-rong;LIU Gao-lin;LI Qin;895
A novel nanoparticle drug delivery system:tumor-exosome encapsulated DOX for breast cancer treatment and cancer metastasis chemopreventionZHOU Yu;XIE Xiao-dong;NIE Hui-fang;JIA Lee;895-896
偶氮鎓二醇盐衍生物抑制肝癌细胞增殖的机制曹梦瑶;陈晶晶;徐静蕾;刘玲;896
NO供体对二乙基亚硝胺诱发大鼠肝癌的抑制作用陈晶晶;曹梦瑶;徐静蕾;刘玲;896
基于非凋亡性程序性死亡的抗肿瘤研究现状陈修平;896-897
ETP类化合物靶向Hsp90-C端抗肿瘤作用以及对其客户蛋白选择性的影响戴佳佳;吴娱;李德海;李静;897
一种新型的靶向BCL9/β-catenin的抗肿瘤和免疫调控的双功能订书肽抑制剂冯梅;朱棣;897
新型靶向eIF4E小分子化合物的合成及抗肿瘤作用机制郭传龙;王立军;897-898
大肠癌DNA修复通路基因和ABCG2基因的多态性与奥沙利铂化疗的环境因素及预后的相关性胡晓云;吴志堃;陈瑜;魏敏杰;吴慧哲;898
非小细胞肺癌亚群的药物靶标研究胡泽平;898
壁虎活性组分对肝癌HepG2细胞糖代谢影响的机制研究黄泽月;王建刚;尹慧萍;王兵兵;898-899
2种小鼠模型用于研究丹参酮ⅡA预防肿瘤细胞肺部的转移李飞杨;卢余盛;899
肿瘤相关巨噬细胞在卵巢癌微环境中的作用及研究进展李晓娟;关秋彤;赵琳;899
乳腺癌耐药细胞通过PGE2促进C/EBPβ与MFG-E8启动子区结合调控巨噬细胞M2表型转化李雪平;王琳;林姝;魏敏杰;赵琳;899
白头翁有效成分通过调控肿瘤相关巨噬细胞极化干预肿瘤发生发展的机制刘鹏;尹力;罗颖颖;陈兰英;900
新型BTK抑制剂对B淋巴瘤细胞系的杀伤活性与功能孟勐;900
CX3CL1/CX3CR1介导的血小板浸润抑制肝癌生长明章银;苗烁;陆濛;刘月;杨如萍;舒丹;朱映;曾祥彬;900
Trichothecin靶向STAT3抑制结肠癌生长转移及作用机制戚欣;戴秀芬;李德;李静;900-901
黄瑞香中活性成分DGD抑制肝癌细胞的作用机制尚新悦;姚国栋;宋少江;901
氧化白藜芦醇在体内外抑制肝癌细胞转移的机制宋英奇;吴喜成;黎荣;冀珍妮;熊文碧;张媛媛;周黎明;901
壁虎超滤组分通过激活Hippo信号通路抑制人肝癌HepG2细胞生长作用王兵兵;黄泽月;尹慧萍;王建刚;901-902
仿生杂交膜纳米药物联合光动力治疗和化疗用于食管癌的研究王卉;沈金秀;孟令伟;祁迎秋;聂广军;902
骨肉瘤的化疗进展研究王晓冬;袁斌;902
连接蛋白32及细胞缝隙连接对卵巢癌细胞顺铂耐药性的影响吴韦黎;蔡少仪;王琴;陶亮;902
去甲肾上腺素对EGFR-TKI耐药性以及Cx32蛋白表达的影响谢洁;彭富华;王琴;陶亮;903
外泌体与乳腺癌CDK4/6抑制剂耐药的关系研究进展颜涵;903
白细胞减少症动物模型优化及代谢组学机制颜磊;徐向平;黄胜;颜冬兰;秦雪梅;田俊生;903
壁虎粗多肽诱导SHSY-5Y细胞凋亡的机制研究尹慧萍;王兵兵;黄泽月;王建刚;903-904
顺铂联合CD47抗体对食管癌移植瘤小鼠的治疗效果尹俭俭;于爽;马昱冉;韩圣娜;张莉蓉;904
基于网络药理学探讨白头翁抗结直肠癌的作用机制尹力;刘鹏;寿斌耀;罗颖颖;陈兰英;904
巨噬细胞外泌体促进乳腺癌细胞增殖和转移于秀艳;张群;韩晴;李慧;毛一卿;王翕;郭红燕;谭焕然;904-905
CLDN3棕榈酰化修饰调控卵巢癌恶性进展的机制研究袁梦;陈小冰;油洁琼;蒋莉;高晓萌;何俏军;曹戟;905
重组免疫毒素bp/CUS的制备及体外抗肿瘤活性测定张彩云;蔡玉梅;熊佳妮;谢捷明;905
黄芩素增强细胞缝隙链接的功能进而增加卵巢癌耐药细胞对顺铂的敏感性郑宁泽;彭富华;樊迪;王琴;905-906专题报告和论文摘要_抗炎抗病毒
Reversible SAHH inhibitor ameliorates psoriasis-like skin inflammation in mice by modulating keratinocyte differentiation and reducing inflammatory infiltration via differentially regulating DNA methylation of GATA3 and LCN2 promotersCHEN Li;LIN Ze-min;HE Shi-jun;ZUO Jian-ping;906
Mechanism of NLRP3 inflammasome modulated hepatocyte pyroptosis in drug-induced liver injuryDONG Hui;YANG Li-hua;ZHAO Jie;ZHANG Jing;BAI Ting;YANG Yong;906-907
Abnormal DNA methylome in multi-generational inheritance programmed by prenatal inflammation exposureGUAN Xiao;DAN Guo-rong;YANG Yao;LAI Wen-jing;DENG You-cai;LI Xiao-hui;907
Mechanism of AMPK modulated NLRP3 inflammasome activation to induce hepatic stellate cells pyroptosisGUO Wen-ying;LIU Jia;LIU Min;LI Jin-zhuo;ZHU Wan-wan;YANG Yong;BAI Ting;907-908
Preliminary study on liver protection and antioxidant active sites of Syringa pinnatifoliaHAO Yi-wei;FAN Lei;CHANG Fu-hou;CAO Xiao-dong;908-909
Metabolomics approach reveals vital role of Huangqi in Huangqi Jianzhong Tang against chronic atrophic gastritis coupled with molecular docking and BAWPLI Xin-qi;LIU Yue-tao;QIN Xue-mei;909
Anti-pruritic and anti-inflammatory effects of natural verbascoside through selective inhibition of temperature-sensitive Ca2+-permeable TRPV3 channelQI Hang;SUN Xiao-ying;WU Han;QU Ya-xuan;WANG Ke-wei;909-910
Dolichosin A, a coumestan isolated from Glycine tabacina, inhibits IL-1β-induced inflammation in SW982 human synovial cells and suppresses RANKL-induced osteoclastogenesis: from network pharmacology to experimental pharmacologyTU Yan-bei;WANG Kai;HE Cheng-wei;910-911
Therapeutic effects and regulation of gut microbiota by dihydrotanshinone on chemotherapy induced colitis in miceWANG Rui;WANG Lin;WANG Shu-mei;DU Guan-hua;911
Effects of baicalin and geniposide on polarization of BV2 microgliaWU Jie;XIANG Jing-yun;WANG Yan;LI Hui-min;ZHOU Shuang;HOU Jian-ping;WANG Bin;911-912
Protective effect of isoforskolin in COPD rat modelXIAO Chuang;CHENG Sha;ZENG De-you;WENG Zhi-ying;YANG Wei-min;912
MAPKs signaling in 5-LOX pathway-associated inflammatory responsesYAN Meng-die;JIA Xiao-xia;LI Cheng-tan;QIU Ya-qing;WANG Yan-fang;ZHANG Li-hui;912-913
CP-25 alleviates rat collagen induced arthritis by regulating T cell subsetsZHANG Ling-ling;TANG Xiao-yu;WANG Chen;HAN Le;ZHANG Xian-zheng;JIN Ling-shu;WEI Wei;913-914
甘草酸单铵和盐酸半胱氨酸对酒精和CCl4诱导的大鼠肝纤维化模型的作用及其机制毕皓植;楚世峰;陈乃宏;914
月见草籽粗提物对致病性枯草芽孢杆菌的抑菌能力陈琦;张可鑫;梁泽华;李佳;姜君;914
肠道菌群通过腺苷A2A受体介导Treg缺失免疫缺陷病何宝坤;914-915
血小板促炎的分子机制和干预药物纪苇;朱德荣;谭瑞;高山;侯雪芹;周延萌;赵晓民;915
蛇六谷葡苷露聚糖对小鼠巨噬RAW264.7细胞免疫调节作用及机制研究季海霞;郝旭亮;刘聪;李佳;吴鑫平;何宇霞;915
CX-10对DSS诱导的小鼠溃疡性结肠炎的作用及其机制冀凯;李新;杜世豪;高振芳;王宇;王增阳;范华英;915-916
人参皂苷Rg1对小鼠急性肝损伤的保护作用李均童;高岩;楚世峰;陈乃宏;916
铃兰毒苷通过PPARγ/NF-κκB信号通路抑制葡聚糖硫酸钠诱导的小鼠实验性结肠炎李明月;张志宏;王喆;马娟;金学军;916
细胞衰老与肾纤维化刘涛;阳群芳;张璇;潘夕春;岑彦艳;覃蓉欣;刘雅;张海港;陈晓红;916
特发性肺纤维化的炎症机制和新型分子靶标钱峰;917
苯甲酰乌头原碱在类风湿关节炎中作用的进展邵鑫;刘福;917
若干天然活性分子对微血管内皮炎症反应的干预作用孙黔云;李敏;郭静;李娇;路青瑜;李朝胜;周英;917
拟人参皂苷-F11对脂多糖所致急性肺损伤小鼠的保护作用王鹏伟;侯颖;张文;吴春福;杨静玉;917-918
丹参素通过调节Nrf2/HO-1和NF-κκB/IκBα信号通路发挥抗大鼠肝纤维化的作用王蓉;王静;宋复兴;李胜男;原永芳;918
血管紧张素Ⅱ2型受体及其信号对类风湿关节炎异常活化的滑膜巨噬细胞的调控作用王鑫铭;许杜娟;魏伟;918
连翘苷通过调控NF-κκB信号途径抑制肝脏星状细胞的活化杨胜乾;李佳行;罗明明;刘娟娟;唐渊;李晓辉;918-919
颈骨康胶囊的活血化瘀及抗炎镇痛作用姚彤;王荣;曹永孝;919
人羊膜间充质干细胞治疗卵巢早衰的作用和机制余丽梅;刘荣霞;张小雨;罗娇;姚观平;范振海;王钰莹;何方;何青;919-920专题报告和论文摘要_代谢疾病
TLR2-deficiency promotes prenatal LPS exposure-induced offspring hyperlipidemiaCAO Da-yan;WANG Wen-jia;CHEN Xin;LI Xiao-hui;920
Adipocyte-derived exosomal miR-27a induces insulin resistance in skeletal muscle through repression of PPARγCHEN Li;YANG Yu;ZHANG Ming;YAO Fan;920-921
Different lipids remodeling signature demonstrated heterogeneity of white adipose tissue browningHE Ping;HOU Bi-yu;YANG Xiu-ying;ZHANG Li;QIANG Gui-fen;DU Guan-hua;921
Improvement of lipid metabolic profile by natural piperine in high-fat diet-fed miceHOU Xing-ming;WANG Li-mei;WANG Ke-wei;921-922
P7C3-A20, a novel neuroprotective agent, treats fatty liver through inducing FGFs in a LKB1/AMPK/CRTC2 pathway-dependent mannerHUA Xia;ZHANG Wen-Jie;SUN Di-Yang;SUN Si-Jia;FU Jiang-tao;ZENG Fei-yan;OUYANG Shen-xi;ZHANG Guo-yan;LI Dong-jie;MIAO Chao-yu;WANG Pei;922
REG3A is a critical regulator involved in tacrolimus-induced toxicity in β cells and remedies tacrolimus-associated NODMLI Sen-lin;ZHANG Zi-jun;ZHOU Hong;XIANG Ming;923
Study on hypoglycemic and hypolipidemic effects of Dayi bacterial prescription teaLI Shuang-long;ZHU Yong-liang;WU Meng-yuan;CHEN Dan-dan;GAO Lin-rui;QIU Xiang-jun;923-924
Study on pharmacodynamics of QiHu preparation for diabetesLI Xiao-li;ZHOU Duan-fang;ZENG Hong-fang;YU Xiao-ping;LONG Liang-yuan;ZHOU Wei-ying;924
FOXO1 inhibition potentiates ischemic angiogenesis in diabetes via suppression of ROCK1/drp1-mediated mitochondrial fissionSHI Yun-di;WU Pin;LI Xue-jun;TIE Lu;924-925
Free fatty acid-induced H2O2 activates TRPM2 to aggravate endothelial insulin resistance via Ca2+-dependent PERK/ATF4/TRB3 cascade in obese miceSUN Lu;LIU Yan-li;YE Fang;XIE Jing-wen;ZENG Jia-wei;QIN Li;XUE Jing;WANG Yi-ting;GUO Kai-min;MA Ming-ming;TANG Yong-bo;LI Xiao-yan;GAO Min;925-926
Evodiamine improves lipid profile in high-fat diet-fed mice by facilitating reverse cholesterol transportWANG Li-mei;HOU Xing-ming;DU Yi-xuan;JIANG Kun;TAN Lin-hai;LUAN Da-zhi;XU Chao-fan;HU Ding-xin;WANG Ke-wei;926
Puerarin alleviates skeletal muscle atrophy in type 1 diabetic ratsYIN Lin;CHEN Xi;LI Na;JIA Wei-hua;WANG Nuo-qi;HOU Bi-yu;QIANG Gui-fen;YANG Xiu-ying;DU Guan-hua;927
High glucose changes mitochondrial dynamics in cultured human glomerular endothelial cellsYU Bai-xue;SHI Yi;927-928
iTRAQ-and LC-MS/MS-based quantitative proteomics reveals potential novel regulators of hepatic glucose metabolismZHANG Wen-jie;SUN Di-yang;LI Guo-Qiang;ZENG Fei-yan;FU Jiang-tao;TONG Jie;MIAO Chao-yu;LI Dong-Jie;WANG Pei;928
白藜芦醇通过诱导自噬减少肥胖小鼠骨骼肌组织GDF8表达的研究曹琼琼;费云飞;陈莉;徐冬梅;徐结苟;鲁云霞;928-929专题报告和论文摘要_新技术新方法
Fast cell counting of brightfield microscopic images based on digital image processingLIN Yue-fei;DIAO Yong;LIU Pei-zhong;DU Yong-zhao;929
New indications for FDA-approved drugs: selective inhibition of growth of Helicobacter pylori by covalent allosteric regulation of ureaseLIU Fan;YU Jing;LI Fang-zhen;XU Jin-yi;WU Fang;929-930
药物靶点鉴定方法学及其在中药活性成分靶点发现中的应用曾克武;930
造血干细胞特异性敲除Foxo1促进NK细胞分化和增殖黄沛;王芳杰;杨耀;赖文静;孟勐;李晓辉;邓有才;930
噬菌体展示技术的概况与应用王欣瑀;于丽凤;贾真;李梓楠;赵琳;930
瑞士球结合电针治疗腰椎间盘突出症的研究王梓林;931
基于Cite Space的IRAK4研究发展与演进分析(1999~2019)肖志彬;敖格日乐图;白图雅;孙丽君;崔嘉禄;常福厚;931
尿酸酶缺失Kunming-DY大鼠的研制张楠;懂鲜祥;云宇;段为钢;931
GABAA受体相关氯离子通道检测方法研究进展张毅;张瑞华;陈学军;王陈;石童;李丽琴;931-932
From older toxic natural products to current drugs and drug candidatesDavid J NEWMAN;932
Screening inhibitory effects of flavonoids isolated from Artemisia sacrorum on lipid accumulation in 3T3-L1 cellsMA Qian-qian;YUAN Hai-dan;PIAO Guang-chun;932
科罗索酸药理作用研究进展张建秀;柳慧哲;朴光春;元海丹;932
第一作者索引933-936
《中国药理学与毒理学杂志》简介937
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